Projects
Projects and Clinical Trials |
Contact |
Research Area A - Risk assessment and sepsis control |
|
|
ALERTS - Effectiveness of a Hospital-wide Educational Programme for Infection control to Reduce the Rate of Healthcare-associated Sepsis |
|
| PEIRAS - Response to Homeostatic Disturbance for Individualized Risk Assessment in Sepsis | Maik Soßdorf |
| CNV Sepsis - Impact of copy number variations within the defensin locus on 8p23 and the cystathionine beta synthase gene in human sepsis and sepsis complications | Christoph Sponholz |
| OSARST - Obstructive sleep apnea postoperative risk stratification trial | Sven Rupprecht |
| PRED-SEP - Assessment of brain induced immunodepression by markers of autonomic control | Dirk Brämer, Samuel Nowack |
Research Area B - Novel diagnostic tools |
|
| Lab-ALERTS - Risk Assessment and Pathogen Identification in sytemic inflammation using Mass-Spectroscopy | Michael Kiehntopf |
| ACTION - Prognostic and Diagnostic Relevance of Bacterial DNA Detection in Patients with Liver cirrhosis and Ascites at Risk for Spontaneous Bacterial Peritonitis - a prospective multicenter study |
|
| SPADE - Novel Diagnostic Tools for Culture-Independent Sepsis Pathogen Detection | Ute Neugebauer |
| ARAS - Androgen-Regulation of the Sepsis response: Beneficial role of androgen receptor antagonists? | Daniela Röll, Aria Baniahmad |
| TransSeptomics - Integrative analysis of omics data from experimental and clinical sepsis in a translational approach towards individualized prevention, diagnosis and therapy | Sandro Lambeck |
Research Area C - Acute Care |
|
| MEDUSA - Medical Education for Sepsis Source Control and Antibiotics | Frank Bloos, Konrad Reinhart |
| PCT-Diagnostic - Meta-analysis of procalcitonin (PCT) as diagnostic test for sepsis and ist clinical value in adults and children | Christina Wacker, Peter Schlattmann |
| PCT-Therapy - Meta-Analysis of Procalcitonin (PCT) guided therapy of sepsis | Anna Prkno, Peter Schlattmann |
| EIDECS - (End-of-life DECisionmaking in patients with Sepsis) Improving patient-centered end-of-life care in patients with sepsis-related organ failure: a time-series intervention analysis | Christiane Hartog |
Research Area D - Sepsis related organ failure |
|
| PRAISE - Prospective, multicenter, randomized, double-blind, placebo-controlled study for the evaluation of IloproSt in the Early postoperative period after liver transplantation | Falk Rauchfuß |
| HHDP - Heme, heme degradation products and systems biology of sepsis-induced organ failure | Michael Bauer |
| HIFMORG - Role of HIF-1α and Morg1 in sepsis induced injury | Gunter Wolf |
| SMAD2 - Analysis of the mechanisms of chronification in a sepsis model in a cell- or organ-specific SMAD2 k.o. mouse | Raimund Kinne |
| CANDIDA - Pathogen-host interaction during infection with candida albicans and its progression to sepsis | Falk Gonnert, Bernhard Hube |
| SomatostatinR - The somatostatin receptor 2A as a possible therapeutic target in sepsis and associated liver dysfunction | Isabell Lenhardt, Amelie Lupp |
| PI3Kgamma - Dual role of PI3Kgamma in pathogenesis of septic cardiomyopathy | Bernadin Dongmo, Reinhard Wetzker |
| ROSISEP - Role of reactive oxygen species (ROS) in septic myocardial dysfunction | Andreas Finkensieper |
| ADAMTS13 - Sepsis-associated Microthrombus Formation: Processing and Secretion of von-Willebrand Factor Cleaving Protease, ADAMTS13 | Michael Ekaney, Ralf Claus |
| Thrombomodulin - Role of the Lectin-like Domain of Thrombomodulin in Murine Sepsis-Induced Cardiac Depression |
Sebastian Stehr |
| Liver dysfunction - Sepsis-induced liver failure: Molecular mechanisms and functional significance of excretory dysfunction, altered xenobiotic transformation and impact on critical care pharmacology |
Andreas Kortgen |
Research Area E - Long term sequelae |
|
| ANERGY - Role and mechanisms of T-cell anergy in sepsis | Ignacio Rubio |
| LOSS - Long term immunological sequelae in sepsis-survivors | Katharina Ferrari-Kühne |
| NeuroSOS-NERVE - Neurological Sequelae of Sepsis Investigation of impairment of small somatic and auto-nomic nerve fibres in patients with sepsis | Hubertus Axer |
| NeuroSOS-Dysphagia - Neurological Sequelae of Sepsis: Chronic dysphagia in patients with critical illness polyneuropathy (CIP) or myopathy (CIM) | Jörg Zielske |
| NeuroSOS-SYNC - Neurological Sequelae of Sepsis: Neuronal Oscillations and Synchronization | Albrecht Günther |
| NeuroSOS-CIP - Investigation of nerve and muscle in patients with critical illness polyneuropathy (CIP) using 3-Tesla-MRI | Hubertus Axer |
| SEPMech - Long Term Impact of Sepsis Associated Encephalopathy: Mechanisms and Therapeutic Options | Silvio Schmidt |
| PAIN - Incidence, characteristics, and functional interference of pain in sepsis survivors | Winfried Meißner |
| SMOOTH - Sepsis survivors Monitoring and cOordination in OutpatienT Health care - Improving long-term care for patients after sepsis | Konrad Schmidt, Jochen Gensichen |
| LOS - Long term Cognitive Outcome after Sepsis - A multicenter study | Farsin Hamzei |
| CRISIS - Stress disorders following prolonged critical illness in patients with severe sepsis | Gloria-Beatrice Wintermann, Jenny Rosendahl |
Research Area F - Public Health |
|
| COST-ALERTS - ALERTS Subproject | Michael Hartmann |
Overarching projects |
|
| CSCC Biobank | Michael Kiehntopf |
| CSCC Prozess Controlling | Johannes Ruhland |
